ceramide kinase; hCERK; acylsphingosine kinase; lipid kinase 4; LK4 (CERK, KIAA1646)

Function

• phosphorylation of ceramide to form ceramide 1-phosphate

Structure

contains 1 DAGKc domain

Compartment

cytoplasm & membrane-associated

Expression

• expressed in heart, brain, skeletal muscle, kidney & liver > leukocytes, thymus > spleen, small intestine, placenta, lung

More general terms

• kinase or ATP-phosphotransferase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64781
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:64781
• OMIM: https://mirror.omim.org/entry/610307
• UniProt: http://www.uniprot.org/uniprot/Q8TCT0.html