galactokinase (GALK1, GALK)

Function

• major enzyme for galactose metabolism
• galactose metabolism, 1st step

ATP + D-galactose <--> ADP + alpha-D-galactose 1-phosphate

Structure

belongs to the GHMP kinase family. GalK subfamily

Pathology

• defects in GALK1 are the cause of galactosemia 2

Laboratory

• galactokinase in erythrocytes
• galactokinase in leukocytes

More general terms

• kinase or ATP-phosphotransferase

More specific terms

• N-acetylgalactosamine kinase (galNAc kinase, galactokinase 2, GALK2, GK2)

Additional terms

• N-acetylgalactosamine kinase (galNAc kinase, galactokinase 2, GALK2, GK2)

Database

• OMIM: https://mirror.omim.org/entry/230200
• OMIM: https://mirror.omim.org/entry/604313
• UniProt: http://www.uniprot.org/uniprot/P51570.html