glutathione S-transferase mu-4; M4; GSTM4-4; GTS-mu2; GST class-mu 4; GTS-Mu2 (GSTM4)

Function

• conjugation of reduced glutathione to a wide number of exogenous & endogenous hydrophobic electrophiles
• active on 1-chloro-2,4-dinitrobenzene

RX + glutathione <--> HX + R-S-glutathione

Structure

• homodimer
• belongs to the GST superfamily, Mu family

Compartment

cytoplasm

Alternative splicing

named isoforms=2

Expression

expressed in a wide variety of tissues

More general terms

• glutathione S-transferase mu

Database

• UniProt: http://www.uniprot.org/uniprot/Q03013.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2948
• OMIM: https://mirror.omim.org/entry/138333
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2948