sialate O-acetylesterase (sialic acid-specific 9-O-acetylesterase, H-Lse, SIAE, YSG2)

Function

• catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid

N-acetyl-O-acetylneuraminate + H2O
            <-->
N-acetylneuraminate + acetate

Compartment

lysosome (probable)

Alternative splicing

named isoforms=3

Expression

• widely expressed with high expression in testis, prostate, & colon

More general terms

• carboxylase (carboxylic ester hydrolase)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HAT2.html