Aflatoxin B1 aldehyde reductase member 4 (AKR7A4, AFAR3, AKR7L)

Function

• can reduce dialdehyde protein-binding form of aflatoxin B1 to the non-binding aflatoxin B1 dialcohol
• may be involved in protection of liver against the toxic & carcinogenic effects of aflatoxin B1 (putative)

Structure

belongs to the aldo/keto reductase 2 family

Expression

Mainly expressed in uterus

More general terms

• aldo-keto reductase

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NHP1.html