bestrophin-4 (vitelliform macular dystrophy 2-like protein 2, BEST4, VMD2L2)

Function

• forms Ca+2-sensitive Cl- channels
• may conduct other physiologically significant anions such as HCO3-

Structure

• belongs to the bestrophin family

Compartment

cell membrane

Expression

• expressed in colon > fetal brain, spinal cord, retina, lung, trachea, testis, placenta

More general terms

• bestrophin

Database

• OMIM: https://mirror.omim.org/entry/607336
• UniProt: http://www.uniprot.org/uniprot/Q8NFU0.html