bestrophin-2 (vitelliform macular dystrophy 2-like protein 1, BEST2, VMD2L1)

Function

• forms Ca+2-sensitive Cl- channels
• may conduct other physiologically significant anions such as HCO3-

Structure

• belongs to the bestrophin family

Compartment

cell membrane

Expression

• largely confined to the retinal pigment epithelium & colon

More general terms

• bestrophin

Database

• OMIM: https://mirror.omim.org/entry/607335
• UniProt: http://www.uniprot.org/uniprot/Q8NFU1.html