bestrophin-3 (vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3)

Function

• forms Ca+2-sensitive Cl- channels
• may conduct other physiologically significant anions, i.e. HCO3-

Structure

• belongs to the bestrophin family

Compartment

cell membrane

Alternative splicing

named isoforms=4

Expression

• expressed in skeletal muscle > brain, spinal cord, bone marrow, retina

More general terms

• bestrophin

Database

• OMIM: https://mirror.omim.org/entry/607337
• UniProt: http://www.uniprot.org/uniprot/Q8N1M1.html