tripartite motif-containing protein 54 (muscle-specific RING finger protein 3, MuRF3, MURF-3, muscle-specific RING finger protein, MuRF, RING finger protein 30, TRIM54, MURF, MURF3, RNF30)

Function

• binds & stabilizes microtubules during myotube formation (putative)
• interacts with tubulin
• interacts with TRIM63, TRIM55

Structure

• homo-oligomer & hetero-oligomer
• contains 1 B box-type zinc finger
• contains 1 COS domain
• contains 1 RING-type zinc finger

Compartment

• cytoplasm
• associates with microtubules
• localizes to the Z-lines in skeletal muscles

Alternative splicing

named isoforms=2

Expression

• specifically expressed in heart muscle & skeletal muscle

More general terms

• tripartite motif-containing protein (trim protein)

Database

• OMIM: https://mirror.omim.org/entry/606474
• UniProt: http://www.uniprot.org/uniprot/Q9BYV2.html