tripartite motif-containing protein 47; gene overexpressed in astrocytoma protein; RING finger protein 100 (TRIM47, GOA, RNF100)
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Structure
- belongs to the TRIM/RBCC family
- contains 1 B box-type Zn+2 finger
- contains 1 B30.2/SPRY domain
- contains 1 RING-type Zn+2 finger
Compartment
Expression
- low expression in most tissues
- higher expression in kidney tubular cells
Pathology
- overexpressed in astrocytoma tumor cells