tripartite motif-containing protein 16; estrogen-responsive B box protein (TRIM16 EBBP)

Function

• may play a role in the regulation of keratinocyte differentiation

Structure

• belongs to the TRIM/RBCC family
• contains 2 B box-type Zn+2 fingers
• contains 1 B30.2/SPRY domain

Compartment

cytoplasm

Alternative splicing

named isoforms=2

Expression

• highest levels found in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle & mammary gland
• more highly expressed in fetus than in corresponding adult tissues
• expressed in basal keratinocytes

More general terms

• tripartite motif-containing protein (trim protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10626
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10626
• OMIM: https://mirror.omim.org/entry/609505
• UniProt: http://www.uniprot.org/uniprot/O95361.html