ATP-dependent RNA helicase DDX19B; DEAD box protein 19B; DEAD box RNA helicase DEAD5 (DDX19B, DBP5, DDX19)

Function

• ATP-dependent RNA helicase involved in mRNA export from the nucleus
• ATP + H2O = ADP + phosphate
• interacts with NUP214

Structure

• belongs to the DEAD box helicase family, DDX19/DBP5 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

• cytoplasm, nucleus, nuclear pore complex, nuclear membrane
• peripheral membrane protein; cytoplasmic side
• nuclear pore complex cytoplasmic fibrils

Alternative splicing

named isoforms=2

More general terms

• DEAD box ATP-dependent helicase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11269
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11269
• OMIM: https://mirror.omim.org/entry/605812
• UniProt: http://www.uniprot.org/uniprot/Q9UMR2.html