ATP-dependent RNA helicase DDX10; DEAD box protein 10 (DDX10)

Function

• putative ATP-dependent RNA helicase
• ATP + H2O = ADP + phosphate

Structure

• the Q motif is unique to & characteristic of the DEAD box family of RNA helicases & controls ATP binding & hydrolysis
• belongs to the DEAD box helicase family, DDX10/DBP4 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Expression

• widely expressed
• high expression in testis

More general terms

• DEAD box ATP-dependent helicase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1662
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1662
• OMIM: https://mirror.omim.org/entry/601235
• UniProt: http://www.uniprot.org/uniprot/Q13206.html