elastase-2A or pancreatic elastase IIA (ELA2A, CELA2A)

Function

• hydrolysis of elastin
• interacts with CPA1
• preferential cleavage: Leu-|-Xaa, Met-|-Xaa & Phe-|-Xaa

Structure

• belongs to the peptidase S1 family, elastase subfamily
• contains 1 peptidase S1 domain

Compartment

secreted

Expression

pancreas

More general terms

• serine protease elastase

Database

• UniProt: http://www.uniprot.org/uniprot/P08217.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=63036