Uracil phosphoribosyltransferase (UMP pyrophosphorylase, UPRTase, UPRT)

Function

• pyrimidine salvage pathway

UMP + diphosphate
     <-->
uracil + 5-phospho-alpha-D-ribose 1-diphosphate

Structure

belongs to the UPRTase family

Compartment

cytoplasm, nucleus

Alternative splicing

named isoforms=3

Expression

• highly expressed in leukocytes, liver, spleen & thymus
• lower expression in brain, lung & skeletal muscle

More general terms

• phosphoribosyltransferase

Database

• UniProt: http://www.uniprot.org/uniprot/Q96BW1.html