phospholysine phosphohistidine inorganic pyrophosphate phosphatase (hLHPP, LHPP)

Function

-..........-

diphosphate + H2O <--> 2 phosphate

Kinetic parameters:

• Optimum pH is 7.0 for PNP, & 5.5 for PPi

Structure

• homodimer
• belongs to the haloacid dehalogenase-like hydrolase superfamily

Expression

expressed in liver, kidney & moderately in brain

More general terms

• phosphodiesterase

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H008.html