2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase; (CNP)

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^[1]^[2]

Function

nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate

Structure

belongs to the cyclic nucleotide phosphodiesterase family

Compartment

membrane, melanosome
firmly bound to membrane structures of brain white matter

Alternative splicing

named isoforms=2

Expression

within the rat CNS, preferentially expressed in oligodendrocytes^[2]

More general terms

cyclic nucleotide phosphodiesterase

References

↑ UniProt http://www.uniprot.org/uniprot/P09543.html
↑ ^2.0 ^2.1 Thug I, Gouw A, Dizon P, Zhao L, Zhang H, Zawaideh R, Solovyeva A, Timiras PS Long-term effects of growth factors on neuroglia: proliferation, dedifferentiation and neurogenesis Aging: Mechanisms and Prevention 34th Annual Meeting of the American Aging Association June 3-6, 2005, Oakland CA

Database

Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1267
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1267
OMIM: https://mirror.omim.org/entry/123830
UniProt: http://www.uniprot.org/uniprot/P09543.html

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