chromosomal translocation t(X;17)(p11;q25)

Introduction

• chromosomal translocation t(X;17)(p11;q25) involving ASPSCR1 & TFE3 is recurrent in alveolar soft part sarcoma (ASPS) & may be a cause of papillary renal cell carcinoma (PRCC)
• translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein

More general terms

• chromosomal translocation

Additional terms

• alveolar soft part sarcoma
• renal cell carcinoma (hypernephroma, Grawitz tumor)