Parkinson's disease 7 (PARK7)

Genetics

• autosomal-recessive
• caused by defects in DJ1 gene

Clinical manifestations

• early-onset parkinsonism, before age 40-50
• slow progression
• initial good response to Sinemet

More general terms

• familial Parkinson's disease

Additional terms

• protein deglycase DJ-1; DJ-1; oncogene DJ1; parkinson disease protein 7 (PARK7)

Database

• OMIM: https://mirror.omim.org/entry/606324