familial Alzheimer's disease [PS2/ASN141ILE]

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Introduction

One of 2 genes encoding seven transmembrane proteins associated with AD. Found in Volga German kindred.

More general terms

References

  1. Levy-Lahad E, Wijsman EM, Nemens E, Anderson L, Goddard KA, Weber JL, Bird TD, Schellenberg GD. A familial Alzheimer's disease locus on chromosome 1. Science. 1995 Aug 18;269(5226):970-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7638621
  2. Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K, et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science. 1995 Aug 18;269(5226):973-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7638622