Ca+2 homeostasis endoplasmic reticulum protein (SR-related CTD associated factor 6, ERPROT 213-21, CHERP, DAN26, SCAF6)

Function

• role in Ca+2 homeostasis, growth & proliferation

Structure

• contains 1 G-patch domain
• contains 1 RPR domain
• contains 1 SURP motif repeat

Compartment

• cytoplasm, cytoplasm, perinuclear region
• endoplasmic reticulum.
• distributed throughout the cytoplasm & also localizes to the perinuclear region of both human erythroleukemia (HEL) cells & Jurkat cells
• colocalizes with ITPR1

Alternative splicing

named isoforms=2

Expression

• expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac & skeletal muscle, & in cultured HEL & Dami cells

More general terms

• uncharacterized protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IWX8.html