nicotinic receptor alpha4-beta2

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Introduction

Nicotinic receptor believed to mediate addictive properties of properties of nicotine.

More general terms

Additional terms

References

  1. Internal Medicine News 39(8): April 15, 2006
  2. Tapper AR et al, Nicotine activation of alpha4 receptors: sufficient for reward, tolerance, and sensitization. Science 2004; 306:1019
  3. Piccionto MR et al, Acetylcholine receptors containing the beta2 receptor are involved in the reinforcing properties of nicotine. Nature 1998; 291:173
  4. Coe JW et al, In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)cystine Bioog Med Chem Lett 2005; 15:2974