Richter's syndrome; Richter transformation

Introduction

Chronic lymphocytic leukemia that has transformed into diffuse large cell lymphoma.

Clinical manifestations

• fever
• massive asymmetric adenopathy
• splenomegaly

Management

Prognosis: poor

More general terms

• syndrome

Additional terms

• chronic lymphocytic leukemia (CLL)
• diffuse large B-cell lymphoma (DLBCL)