intravenous (IV) extravasation

Management

• hyaluronidase
  • reconstitute 150 unit vial of lyophylized powder with 1 mL of normal saline
  • take 0.1 mL of this solution & dilute with 0.9 mL of normal saline to yield 15 units/mL
  • five 0.2 mL injections are made SC or intradermally into the extravasation site at the leading edge using a 25 or 26 gauge needle
  • change needle after each injection
  • apply heat immediately for 1 hour
  • repeat 4 times/day for 3-5 days

More general terms

• extravasation