protocol for oral desensitization to beta lactam antibiotics

Procedure

Table

time (min)	dose (mg)	cumulative dose (mg)
0	0.05	0.05
15	0.1	0.15
30	0.2	0.35
45	0.4	0.35
60	0.8	0.75
75	1.6	1.55
90	3.2	3.15
105	6.0	6.35
120	12.0	24.35
135	24.0	48.35
150	50.0	98.35
165	100.0	198.35
180	200.0	398.35
195	400.0	798.35

After completion, observe patient for 15 minutes. If no problems, administer 1 g of same agent intravenously.

The drug suspension 0.5-50 mg/mL is diluted in 30 mL of water for ingestion

More general terms

• clinical procedure
• protocol