hermaphrodite

Introduction

An organism with both male & female sexual organs.

Pathology

• a true hermaphrodite must have both mature ovarian & mature testicular tissue with histologic evidence of follicles & tubules, respectively.

Genetics

• associated with defects in SRY (true hermaphroditism)
• genetically heterogeneous
• genotype of most affected individuals is 46,XX, but many have 46,XY or a mosaic of 46,XX/46,XY
• can be caused by chromosomal translocation

More general terms

• congenital anomaly (birth defect)

Database

• OMIM: https://mirror.omim.org/entry/235600