agammaglobulinemia type 2

Pathology

• primary immunodeficiency
• early block of B-cell development

Genetics

• associated with defects in IGLL1

Clinical manifestations

• severe infections in the first years of life

Laboratory

• low or absent serum antibodies (serum IgG) (serum IgM)
• & low B-cell count in blood

More general terms

• agammaglobulinemia
• genetic disease of the immune system

Database

• OMIM: https://mirror.omim.org/entry/613500