Witkop syndrome; tooth-&-nail syndrome; dysplasia of nails with hypodontia

Genetics

• autosomal dominant
• associated with defects in MSX1

Clinical manifestations

• little involvement of hair & sweat glands
• teeth are not as severely affected compared with anhidrotic ectodermal dysplasia

More general terms

• ectodermal dysplasia
• genetic syndrome (multisystem disorder)

Database

• OMIM: https://mirror.omim.org/entry/189500